Gout and Uric Acid Control

Tom Richardson, Co-Founder and President, TSN
Tom Richardson, Co-Founder and President, Top Secret Nutrition

We asked Tom to write this article to explain the condition known as gout, its connection to uric acid levels in the blood, and a new product which he developed to help combat the pain associated with gout.

What is Gout?

Gout is a form of arthritis — an inflammation of the joints — that causes sudden, severe attacks of pain, tenderness, redness, warmth, and swelling in some joints. It usually affects one joint at a time, although it can be in several joints at once. Gout is a rheumatic disease which is a result of uric acid crystals (monosodium urate) being deposited in tissues and fluids within the body. This process is caused by an overproduction and/or under excretion of uric acid. Despite the severity of gout, just 10 percent of sufferers are getting needed, ongoing treatment. Those who do seek medical treatment are put on drugs to reduce the production of uric acid.

High levels of uric acid also lead to the creation of kidney stones, another painful affliction.

What is Uric Acid?

As cells die, they release substances called purines, which are also found in some foods. Purines are converted to uric acid via the enzyme xanthane oxidase(see below). Two popular pharmaceutical drugs to combat gout are Allopurinol and Febuxostat and both are xanthine oxidase inhibitors. The side effects of these drugs can include difficulty breathing, unusual bleeding, vomiting, nausea, or severe skin rash. They may even interfere with other medications.

Introducing Uric-Control™

A natural dietary supplement to combat high uric acid levels and associated pain, Uric-Control™ is made up of three ingredients. Special care was taken during the formulation of the product to make sure that each ingredient was included at the levels dictated by research to insure effectiveness. The three ingredients are:

1.  CherryPURE® – CherryPURE® Tart Cherry powder is the premier tart cherry material in the marketplace and the only tart cherry source backed by ingredient specific clinical studies. Tart cherry:

  • Helps mitigate pain and inflammation – In 2012, scientists measured the impacts of tart cherry on serum inflammatory biomarkers among inflammatory osteoarthritis (Patients with inflammatory or erosive osteoarthritis are those who suffer from sudden signs of inflammation, such as redness, pain, and swelling.) Among those patients consuming the tart cherry juice, there was a statistically significant decrease in inflammation, indicated by reduced levels of C-reactive protein (CRP). This research demonstrates that tart cherry juice provides osteoarthritis patients with anti-inflammatory activity without the adverse effects and risks of traditional arthritis medications.
  • Inhibits Xanthine Oxidase – A study conducted by scientists at Boston University found that intake of cherry extract reduced the risk of gout attacks in those who suffered recurrent gout attacks by 45%.

2.  Celery Seed Extract (85% 3nB)

  • Helps reduce pain and inflammation from gout. While research on celery seed extract is still in its early stages, researchers are particularly excited about the active ingredient known as phthalides (pronounced thalides).  The chemical abbreviation is 3nB and these substances are thought to be anti-inflammatory agents. They work by inhibiting pro-inflammatory prostaglandins to reduce pain resulting from the body’s inflammatory response to degenerative conditions (Aspirin and aspirin-like drugs use the same pain-killing mechanism).
  • In one 12-week pilot study, 15 subjects (suffering from osteoarthritis, osteoporosis, or gout) received 34 mg of a proprietary celery seed extract standardized to contain 85 percent phthalides twice daily. Participants experienced significant pain relief after three weeks, and most achieved maximum benefit after six weeks of use.
  • In a larger 70-patient study, participants received 75 mg of celery extract twice daily for three weeks. At this higher dosage, subjects reported even better results than in the pilot study. Statistically and clinically significant reductions were noted in pain scores, mobility, and quality of life.

3.  Ayurica Terminalia Bellerica

  • Inhibits Xanthine Oxidase – Fortunately for gout sufferers and those with uric acid buildup, scientists have demonstrated the effectiveness of a natural alternative to drugs with a strong history of traditional Ayurvedic use and no reported side effects. Derived from the edible fruit of the Terminalia bellerica tree, this tannin-rich extract is believed to inhibit xanthine oxidase, an enzyme involved in the synthesis of uric acid.
  • A randomized, double blind, and placebo-controlled human clinical trial has recently confirmed the dose-dependent action of Terminalia bellerica extract in decreasing blood levels of uric acid. In volunteers with elevated levels, one capsule of 500 mg of Terminalia bellerica extract, taken twice daily, decreased uric acid by a mean of 27.59%. This decrease in uric acid levels enabled 88.8% of the people in the study arm taking the extract to achieve targeted uric acid serum levels…with no side effects

Summary

If you, or anybody you know, suffers with gout like symptoms, consult with your physician, and try out Uric-Control.  Your can purchase it HERE.  Let us know how you like it and how well it works for you.

 

Tom Richardson

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